- Inoperable tumors close to critical structure
- Uses high voltage, low energy electrical pulses to achieve tissue necrosis
- No heat sink effect
- Does not rely on heat to ablate tissue
NANO KNIFE - A UNIQUE ALTERNATIVE TO THERMAL ABLATION
NanoKnife - What is it?
An ablation procedure that uses low energy electrical pulses to create defects (pores) in cell membranes, resulting in loss of homeostasis and subsequent cell death.
- Uses high voltage, but low energy direct current (LEDC) – and does not rely on heat to create the tissue effect. This allows physicians to treat soft tissue near critical structures, like blood vessels, ducts, or lymph nodes.
- Well suited for patients who have non- resectable soft tissue disease near critical structures and who otherwise have no other treatment option given the location of their disease.
How NanoKnife® Technology Works ?
- Rapid series of short, electrical pulses
- Low energy direct current (LEDC).
- Ablation effect is not thermal
- Nano‐sized defects (“pores”) created in cell membrane
- Cell death occurs (mimics natural cell death).
- Resulting debris eliminated through vascular pathways
NanoKnife® : Clinical Advantages
- Provides potential to spare critical structures – vasculature and ducts remain intact
- Ablated tissue removed by the body’s natural processes within weeks (mimics natural cell death)
- Provides predictable zone of ablation (treatment area)
- Patients report experiencing minimal to no post procedural pain
NanoKnife: Where is it used?
Inoperable tumors of:
- For ablating tumors close to critical structures or tumors close to blood vessels.